DESCRIPTION OF DATABASE

The following database has been compiled from various public sources found online. Examples include, but not limited to Clinicaltrials.gov, NIH, JDRF, ADA, the Helmsley Trust, and Iacocca. None of the records found within our database are proprietary to the Frederick Banting Foundation. Our intentions are to simply provide interested parties with a one stop source for researching, tracking and analyzing medical research related to type 1 diabetes. Our group has attempted to further reduce the burden of this task by aggregating all public records found in to this central repository and later categorizing each according to the focus of each project. Only projects with the intentions of materializing into a therapeutic solution for addressing the disease directly are included in our data set. This is an important point, as no work related to complications, type 2 diabetes, surveys, behavioral, events/outreach (such as conferences, summer camp, and educational) or facility overhead will be found in our database. If the research project will not lead to some kind of clinical application, therapy, drug or product, then it will not be found here.

Data Source

Our group has scoured numerous databases that are publically available. While we do not make claims to this database holding every possible record of funded projects related to T1D, we do cover all the major funding sources and feel confident that we have captured the majority of all funded research. Some of the public sources where we have aggregated our data from, include:

  • American Diabetes Association (ADA) – www.diabetes.org
  • The Helmsley Trust – Helmsleytrust.org
  • Iacocca Family Foundation – www.iacoccafoundation.org
  • JDRF – JDRF.org
  • NIH Database – Report.nih.gov
  • NSF / NASA Database – Research.gov
  • All Clinical Trials – clinicaltrials.gov

Description of Categories

The categories are primarily centered on distinguishing between early, basic science where an investigator is attempting to uncover new facts that could lead to testing a therapy and those that are beyond basic research and are testing a chosen therapy that could lead to clinical application. Another way to say this is the difference between basic and translational research. A user can start by selecting (1) Practical Cure; innovations offering a medium to long-term respite from insulin injections, (2) Treatment; technologies that improve the ease and accuracy of care or (3) Other; projects that fall more within the early, basic science category. Each of these has coordinating sub-categories as follows:

I.     Treatment

  1. Post Meal Glucose Control (Anything looking to correct the delayed action of subcutaneous insulin delivery and resulting BG excursions. Including some devices, hormones, incretins, anti-diabetic drugs, etc.)
  2. Devices (CGMs, Pumps, Artificial Pancreas, etc.)
  3. Other Drug Therapies (drugs that don’t fall into other category like various insulin products available in the market)
  4. Treatment Regimen (studies looking to understand how to better manage T1D with a treatment protocol)

II.     Practical Cure

  1. Auto-Immune Correction
  2. Beta Cell Enhancement, Regeneration, Replacement (includes islet cell transplants, encapsulation, methods for producing beta cells like stem cells, etc.)

III.   Other

  1. T1D Disease Pathogenesis (understanding the cause of T1D)
  2. Basic Physiological Effect of T1D (how T1D affects other biological factors)
  3. Other (a catch all category that includes dietary, epidemiology, etc.)

If there are any questions or concerns on the content found in our database or with the accuracy of the records please do not hesitate to contact us. Through the help and participation of the scientific community we only hope to improve this tool. Please reach out to Joe Hernandez with any feedback at joe@bantingfoundation.com.